Overview
Jaundice is a yellow discoloration of the skin and the whites of the eyes caused by a build-up of bilirubin, a pigment produced when red blood cells break down. It is a sign of an underlying problem in the liver, bile ducts or blood, rather than a disease on its own. Jaundice in an adult always needs prompt medical assessment.
Symptoms
Yellow skin and yellow whites of the eyes
Dark, tea-colored urine
Pale, clay-colored stools
Itching of the skin
Fatigue, nausea or loss of appetite
Abdominal pain, fever or weight loss
Common Causes
Viral hepatitis and other liver infections
Alcohol-related, fatty or drug-induced liver injury
Gallstones blocking the bile duct
Tumors of the pancreas, bile ducts or liver
Cirrhosis and other chronic liver diseases
Breakdown of red blood cells (hemolysis) or inherited conditions such as Gilbert syndrome
Self-Care Tips
Seek medical assessment on the same day you notice yellowing
Avoid alcohol completely until a cause is found
Do not take new herbal products, supplements or medicines without medical advice
Bring a list of every medicine and supplement you use
Drink fluids and eat light meals if you feel nauseated
Follow your doctor's advice on tests and follow-up closely
When to See a Doctor
Jaundice needs same-day medical assessment. Go to the emergency department immediately if jaundice comes with fever and chills, severe abdominal pain, confusion or unusual drowsiness, vomiting blood, black stools, or easy bruising and bleeding. Do not wait for it to clear on its own.
How doctors investigate it
Your doctor will ask about the onset, medications, alcohol, travel, and any itching, pain or dark urine, then examine you. Blood tests measure bilirubin and liver enzymes and check blood counts and clotting. Ultrasound is usually the first imaging test to look for gallstones, bile duct dilation or liver changes. Further tests such as MRCP, CT, or endoscopic procedures to examine the bile ducts may be needed depending on the findings.
Treatment options
Jaundice is treated by treating its cause. A blocked bile duct may be opened with an endoscopic procedure or surgery, and viral hepatitis may be managed with supportive care or specific antiviral treatment depending on the virus. Medicine- or alcohol-related injury requires stopping the trigger under medical guidance. Chronic liver disease needs long-term follow-up with a specialist.
Frequently Asked Questions
Is jaundice a disease?
Does yellow skin always mean a serious liver disease?
Can yellow skin from eating too many carrots be mistaken for jaundice?
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